Model-Based Preparative Chromatography Process Development in the QbD Paradigm / Arne Staby, Satinder Ahuja, Anurag S Rathore -- Adsorption Isotherms / Jørgen M Mollerup -- Simulation of Process Chromatography / Bernt Nilsson, Niklas Andersson -- Simplified Methods Based on Mechanistic Models for Understanding and Designing Chromatography Processes for Proteins and Other Biological Products-Yamamoto Models and Yamamoto Approach / Noriko Yoshimoto, Shuichi Yamamoto -- Development of Continuous Capture Steps in Bioprocess Applications / Frank Riske, Tom Ransohoff -- Computational Modeling in Bioprocess Development / Francis Insaidoo, Suvrajit Banerjee, David Roush, Steven Cramer -- Chromatographic Scale-Up on a Volume Basis / Ernst B Hansen -- Scaling Up Industrial Protein Chromatography / Chris Antoniou, Justin McCue, Venkatesh Natarajan, Jörg Thömmes, Qing Sarah Yuan -- High-Throughput Process Development / Silvia M Pirrung, Marcel Ottens -- High-Throughput Column Chromatography Performed on Liquid Handling Stations / Patrick Diederich, Jürgen Hubbuch -- Lab-Scale Development of Chromatography Processes / Hong Li, Jennifer Pollard, Nihal Tugcu -- Problem Solving by Using Modeling / Martin P Breil, Søren S Frederiksen, Steffen Kidal, Thomas B Hansen -- Modeling Preparative Cation Exchange Chromatography of Monoclonal Antibodies / Stephen Hunt, Trent Larsen, Robert J Todd -- Model-Based Process Development in the Biopharmaceutical Industry / Lars Sejergaard, Haleh Ahmadian, Thomas B Hansen, Arne Staby, Ernst B Hansen -- Dynamic Simulations as a Predictive Model for a Multicolumn Chromatography Separation / Marc Bisschops, Mark Brower -- Chemometrics Applications in Process Chromatography / Anurag S Rathore, Sumit K Singh -- Mid-UV Protein Absorption Spectra and Partial Least Squares Regression as Screening and PAT Tool / Sigrid Hansen, Nina Brestrich, Arne Staby, Jürgen Hubbuch -- Recent Progress Toward More Sustainable Biomanufacturing / Milton T W Hearn.

"Preparative Chromatography for Separation of Proteins addresses a wide range of modeling, techniques, strategies, and case studies of industrial separation of proteins and peptides. Covers broad aspects of preparative chromatography with a unique combination of academic and industrial perspectives. Presents Combines modeling with compliantce useing of Quality-by-Design (QbD) approaches including modeling. Features a variety of chromatographic case studies not readily accessible to the general public. Represents an essential reference resource for academic, industrial, and pharmaceutical researchers"-- Provided by publisher.

"Preparative Chromatography for Separation of Proteins addresses a wide range of the most current modeling techniques, strategies, and case studies of industrial separation of proteins and peptides to aid in the efficiency and efficacy of this broadly-used technique in the purification of biopharmaceuticals"-- Provided by publisher.

Includes bibliographical references and index.

Print version record.

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